MiPNO, a new chiral cyclic nitrone for enantioselective amino acid synthesis: the cycloaddition approach.
نویسندگان
چکیده
The resolution of chiral nitrones via derivatization of hydroxylamines was applied to MiPNO, a new, stable, easily prepared chiral cyclic nitrone. The application of MiPNO in totally regio- and diastereo-selective 1,3-dipolar cycloaddition reactions provides an expeditious enantioselective access to unusual gamma-hydroxy alpha-amino acids.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 8 4 شماره
صفحات -
تاریخ انتشار 2010